Acupressure for Cluster Headache involves stimulating specific anatomical points to modulate neural pain pathways and autonomic nervous system activity, potentially through the release of endogenous opioids and neurotransmitters like serotonin and dopamine. The intervention aims to reduce pain perception, decrease sympathetic nervous system activation, and potentially interrupt the pathological neural circuits associated with cluster headache syndrome through non-invasive pressure application to specific meridian points.