Lucent Patient

amitriptyline

Treatment for Cluster Headache

Amitriptyline, a tricyclic antidepressant, modulates neurotransmitter systems by inhibiting serotonin and norepinephrine reuptake, potentially reducing neurogenic inflammation and pain perception in cluster headache. While not a first-line treatment, it may help prevent cluster headache episodes by altering central nervous system pain processing and reducing neurological sensitization.

3.3

AVERAGE EFFICACY

CASE STUDIES

1204

REDDIT COMMENTS

1825

REPORTED SIDE EFFECTS

Case Studies

Coexistence of cluster headache and paroxysmal hemicrania: does it exist? A case report and literature review

5.0

This case study reports a 22-year-old male with simultaneous cluster headache and chronic paroxysmal hemicrania who responded completely to indomethacin treatment, with a literature review of similar coexisting cases.

indomethacinacetaminophennaproxentriptansrizatriptanamitriptylinecalcium channel blockersvalproatebeta blockers

Cluster-status migrainosus with a weekly periodicity responsive to high-flow oxygen: A case report

4.0

A 54-year-old female presented with a unique pattern of cluster headaches that evolved into status migrainosus, which was successfully treated with high-flow 100% oxygen after multiple other treatments failed.

beta blockersvalproateantiepilepticsamitriptylinegabapentinanticonvulsantstriptansbutalbitaloxygen therapy

This case study reports a 22-year-old male with simultaneous cluster headache and chronic paroxysmal hemicrania, both types of attacks responding to indomethacin treatment. The study also reviews literature on the coexistence of these two trigeminal autonomic cephalalgias.

5.0

indomethacinacetaminophennaproxentriptansrizatriptanamitriptylinecalcium channel blockersvalproatebeta blockersh2 blocker

Reddit Comments

KlutzyEmployment1465

3.0

I don’t know what country your In , but in the UK you can get cannabis on medical, which can help . They do Oil , tablets, vapes , etc you don’t have to get flower, If you don’t want to do the mushrooms…. Or you can go down the route of verapam...View more

PsychedelicsCalcium channel blockersAmitriptylineTriptansCaffeine

BLTeague

3.0

The verapimil and the Amytriptaline are not for stopping an active cluster cycle, they are for preventing them from starting. I am on 720 mg/day of verapimil and 50 mg of amitriptolene. I haven’t tried the metocloramide, but I have done sumatriptan...View more

VerapamilAmitriptylineSumatriptanTriptanEmgalityPrednisone

False_Personality259

4.0

I seem to have just come to the end of a 2ish month bout of shadows. For me, shadow only cycles are the norm now. Might be - most probably? - due to medication (Candesartan, Melatonin) and occipital nerve blocks. This time, the shadows were stronger ...View more

CandesartanMelatoninNerve blocksKetogenic dietAmitriptyline

KLB1267

4.0

Fingers crossed for you! Thankyou for sharing Interestingly I frequently crave a good Greek yoghurt! I drink a lot of coffee - never been a soft drink drinker. I've been a longtime vegetarian, but the last thing to go were nitrate heavy cured mea...View more

Occipital nerve ablationAmitriptylineMelatoninOxygen therapy

Reported Side Effects

General side effect

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