aspirin and caffeine
Treatment for Cluster Headache
Aspirin acts as a non-steroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase (COX) enzymes, reducing prostaglandin synthesis and providing analgesic and anti-inflammatory effects. Caffeine acts as an adenosine receptor antagonist, causing vasoconstriction and potentially enhancing the absorption and efficacy of aspirin, while also providing mild analgesic and stimulant properties that can help alleviate cluster headache symptoms.