beta blocker
Treatment for Cluster Headache
Beta blockers, such as propranolol, act by antagonizing beta-adrenergic receptors, thereby reducing sympathetic nervous system activity and decreasing neural excitability. In cluster headache management, they modulate vascular tone and neurogenic inflammation, potentially reducing the frequency and severity of headache episodes by stabilizing cerebral blood vessel reactivity and lowering autonomic nervous system hyperresponsiveness.