biologics
Treatment for Cluster Headache
Biologics like CGRP monoclonal antibodies (e.g., galcanezumab) target and block calcitonin gene-related peptide (CGRP) receptors, which play a critical role in cluster headache pathogenesis. By inhibiting CGRP signaling, these medications reduce neurogenic inflammation and pain transmission, potentially decreasing the frequency and severity of cluster headache attacks.