Lucent Patient

buprenorphine

Treatment for Cluster Headache

Buprenorphine is a partial μ-opioid receptor agonist with unique pharmacological properties that may interrupt cluster headache pathophysiology by modulating nociceptive pathways and providing analgesic effects. Its high receptor affinity and slow dissociation rate can potentially reduce neurogenic inflammation and provide pain relief, while its partial agonist profile minimizes typical opioid-related adverse effects.

2.3

AVERAGE EFFICACY

CASE STUDIES

REDDIT COMMENTS

REPORTED SIDE EFFECTS

Case Studies

No case studies available.

Reddit Comments

TheGrimMinx

3.0

I'm only on 2 mg of buprenorphine. To treat opiod addiction I'd have to be on a MUCH higher dose. I've already tried botox 3 times. It was effective the first 2 times but not the 3rd.

BuprenorphineBotox

Reported Side Effects

General side effect

TheGrimMinx

4.0

Exactly. I'm only on 2 mg of buprenorphine and it's wonderful at controlling pain without the "high."

Buprenorphine

Reported Side Effects

General side effect

spongebobsreal

3.0

It's over $30 per day for the STARTING dose, which is over $10k per year, and the vast majority of insurance plans will pay little of that. Vertex tried 1000s of molecules over 20 years of R&D and finally got this drug approved. Vertex will have...View more

HydrocodoneBuprenorphine

Reported Side Effects

General side effect

SalParadise55

4.0

Huh, thank you all for sharing. I'm on 1800 gaba, 600 lyrica, 8 buprenorphine, and 100 amitriptyline at night. I've been on this for 9 years now. Very minimal side effects overall but lately I've been getting super drowsy during the day. Even wit...View more

GabapentinPregabalinBuprenorphineAmitriptyline

Reported Side Effects

Drowsiness