bupropion
Treatment for Cluster Headache
Bupropion is an atypical antidepressant that acts as a norepinephrine-dopamine reuptake inhibitor (NDRI), which may help modulate pain perception and neurological signaling in cluster headache patients. By increasing levels of norepinephrine and dopamine in the brain, it can potentially reduce the frequency and intensity of cluster headache episodes through its effects on neurotransmitter systems and pain modulation pathways.