Lucent Patient

capsaicin

Treatment for Cluster Headache

Capsaicin, when applied intranasally, acts as a potent TRPV1 receptor agonist that depletes substance P and other neuropeptides from sensory nerve endings, thereby interrupting neurogenic inflammation. Its mechanism involves desensitizing pain receptors and modulating trigeminal nerve signaling, which can provide rapid and significant relief for acute cluster headache symptoms by reducing neuronal hyperexcitability.

3.1

AVERAGE EFFICACY

CASE STUDIES

REDDIT COMMENTS

REPORTED SIDE EFFECTS

Case Studies

No case studies available.

Reddit Comments

icyfignewton

3.0

I take a hot sauce from hot ones, dilute it, soak it up with a q-tip and rub that sucker up in my nose on the flaring side. 🫠 It's not the best way to cope but it brings me relief.

Capsaicin

Reported Side Effects

Nasal irritation

Emotional-Ocelot

3.0

There are studies on zucapsaicin (thing in hot peppers) creams being used for clusters and nerve pain somewhat effectively. So depending on how up to date the doc is, it might be a recommended strategy! (Dunno about the OTHER hot sauce ingredients......View more

Capsaicin

Reported Side Effects

General side effect

Natural_Possible4158

5.0

Hey I’ve had the same issues in the past. I use capsaicin nasal spray before going on the O2. Usually the capsaicin gives me significant reduction in pain for some minutes but in combination with O2 I can Abort an Attack in like 3 Minutes. I sometime...View more

CapsaicinOxygen therapy

Reported Side Effects

Nasal congestionBurning sensation

Sudden_Buffalo_3906

4.0

I use a product called "Sinus Plumber Headache Nasal Spray - headache formula" can get at Amazon, Walmart etc. main ingredient is capsaicin. I can post a link if that is allowed here. Capsaicin helps me better than oxygen. and is a lot less work...View more

CapsaicinAromatherapy

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