Lucent Patient

cgrp antagonists

Treatment for Cluster Headache

CGRP (Calcitonin Gene-Related Peptide) antagonists for Cluster Headache work by blocking the CGRP receptor, which plays a critical role in pain transmission and vasodilation during headache episodes. By inhibiting CGRP's neurogenic inflammatory effects, these medications reduce vascular dilation, neurogenic inflammation, and pain signaling, thereby potentially interrupting or mitigating cluster headache attacks.

3.5

AVERAGE EFFICACY

CASE STUDIES

REDDIT COMMENTS

REPORTED SIDE EFFECTS

Case Studies

No case studies available.

Reddit Comments

figuremeoutt

4.0

I am amazed you haven’t started a CGRP. I prefer to use it with Botox as a preventative and abortive triptan at much higher doses. Metexiline has been suggested for me vs beta blockers, but I respond well to lidocaine, and it seems you may not given ...View more

Cgrp antagonistsBotoxTriptansLidocaine

Reported Side Effects

General side effect

Life-Conference8604

3.0

Migraines are different for everyone. They can also wax and wane in severity so for example I’ll go weeks-months without any symptoms but can regress and have more symptoms. Attacks can last for a long time. My longest attack was roughly 5 months str...View more

BotoxCgrp antagonistsMedicationVitamin supplementsLifestyle modification

Reported Side Effects

Gastrointestinal paralysis

Best_Banana_63

5.0

My little brother has had those for years. He initially started using oxygen therapy. The oxygen is pumped into the nose at as very high rate of speed via a Calendula. He also started chugging Red Bull when he felt a "shadow" coming on. Eventually hi...View more

Oxygen therapyCaffeineCgrp antagonistsVerapamil

Reported Side Effects

General side effect

bluefran1977

4.0

My neurologist told me that typically going from episodic headaches to chronic is due to stress, illness, environment - on top of other triggers like diet. This bore true for me. It’s taken me several years but I have reduced my chronic headache down...View more

Stress reductionTherapyMeditationDietary modificationBotoxCgrp antagonists

Reported Side Effects

None

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