Lucent Patient

combination headache medication

Treatment for Cluster Headache

Combination headache medications for Cluster Headache typically involve triptans (5-HT1B/1D receptor agonists) and NSAIDs, which work synergistically to inhibit neurogenic inflammation and reduce pain signaling. Triptans constrict cranial blood vessels and block pain neuropeptide release, while NSAIDs provide additional anti-inflammatory effects, effectively targeting multiple pathophysiological mechanisms of cluster headache pain.

2.4

AVERAGE EFFICACY

CASE STUDIES

REDDIT COMMENTS

REPORTED SIDE EFFECTS

Case Studies

No case studies available.

Reddit Comments

AuroraFlameCat

4.0

I take maxalt melt oral lyophilisate rizatriptan and migraleve. They work 85% of the time. Didn't see them on your list x

RizatriptanCombination headache medication

Reported Side Effects

General side effect

Kipepeogirl

4.0

I was recommended by a pharmacist to use soluble aspirin as it gets to work quicker than non-soluble. It always helps me, along with a couple of Migraleve.

AspirinCombination headache medication

Reported Side Effects

General side effect

Crazy_Bipolar_2023

4.0

I'm UK based. I first got bad migraines in 2017 (before they were rare) after 3 days of having it, I went to the GP and said how I tried a couple of over the counter meds - paracetamol, ibuprofen migraleve etc - and immediately they handed me a presc...View more

AcetaminophenIbuprofenCombination headache medicationSumatriptan

Reported Side Effects

None

DottiePigs

2.0

Until recently migraleve was my go to, unfortunately that’s stopped working for me now :( Other for go to for headaches that might get worse is Anadin extra (paracetamol, aspirin and caffeine) tablets

Combination headache medicationAcetaminophenAspirinCaffeine

Reported Side Effects

General side effect