domperidone
Treatment for Cluster Headache
Domperidone is a peripheral dopamine D2 receptor antagonist that acts as an antiemetic and prokinetic agent, with potential benefits in cluster headache management. By blocking dopamine receptors in the chemoreceptor trigger zone and gastrointestinal tract, it may help modulate neural pathways and potentially reduce the frequency and intensity of cluster headache episodes, though its precise mechanism in headache treatment is not fully elucidated.