An epidural blood patch for Cluster Headache involves autologous blood injection into the epidural space to seal potential cerebrospinal fluid (CSF) leaks and reduce intracranial hypotension. The procedure creates a localized inflammatory response that promotes fibrin formation and seals CSF leaks, potentially alleviating the neurogenic inflammation associated with severe headache pathophysiology. By stabilizing neural membrane potentials and reducing CSF pressure dynamics, the blood patch can provide symptomatic relief and interrupt the neurological cascade of cluster headache episodes.