ergonomic modification
Treatment for Cluster Headache
Ergotamine tartrate, a vasoconstrictor and serotonin receptor agonist, acts primarily on cerebral blood vessels to reduce neurogenic inflammation and blood vessel dilation associated with cluster headaches. By targeting 5-HT1B/1D receptors, it inhibits neuropeptide release and constricts cranial blood vessels, effectively interrupting the pathophysiological cascade of cluster headache attacks. Its rapid onset and targeted mechanism make it a potent therapeutic intervention for acute cluster headache management.