Lucent Patient

gabapentin

Treatment for Cluster Headache

Gabapentin is an anticonvulsant and analgesic medication that modulates neuronal calcium channels by binding to the α2δ subunit, thereby reducing neuronal excitability and neurotransmitter release. In cluster headache treatment, it potentially interrupts pain signaling pathways and may help stabilize neuronal membranes, potentially reducing the frequency and intensity of headache episodes. Its mechanism suggests it can provide prophylactic benefits by mitigating the underlying neurological dysregulation associated with cluster headaches.

3.2

AVERAGE EFFICACY

CASE STUDIES

699

REDDIT COMMENTS

993

REPORTED SIDE EFFECTS

Case Studies

A triad of cluster-like headaches with delayed development of a macroscopic prolactinoma: A case report

5.0

A 35-year-old man with refractory cluster-like headaches and initially normal brain imaging developed a macroscopic prolactinoma three years after headache onset, with complete resolution of symptoms after treatment with cabergoline.

dopamine agonistsoxygen therapytriptanstriptanibuprofenlidocaineindomethacincalcium channel blockersantiepilepticsmelatoningabapentinmassagetestosterone

Cluster-status migrainosus with a weekly periodicity responsive to high-flow oxygen: A case report

4.0

A 54-year-old female presented with a unique pattern of cluster headaches that evolved into status migrainosus, which was successfully treated with high-flow 100% oxygen after multiple other treatments failed.

beta blockersvalproateantiepilepticsamitriptylinegabapentinanticonvulsantstriptansbutalbitaloxygen therapy

Gabapentin for the Treatment and Prophylaxis of Cluster Headache

4.0

A 38-year-old man with cluster headache refractory to conventional treatments was successfully treated with gabapentin 300 mg twice daily for both treatment and prophylaxis of his headaches.

gabapentin

Chronic Cluster Headache Responding to Gabapentin: A Case Report

5.0

A 28-year-old male with chronic cluster headache who failed multiple conventional treatments achieved complete symptom relief with gabapentin 1800 mg/day after other medications including prednisolone, verapamil, lithium, methysergide, and pizotifen were unsuccessful.

gabapentincorticosteroidcalcium channel blockerslithiummethysergidepizotifen

Reddit Comments

idontknowreally31

2.0

## did any of u use memantine for light and sound induced headaches? how's ur experiences? Hi, I (26/F) have light and sound induced headaches since I used autologous serum. It has been 7 months. It became weak once it has been 6 months but still If ...View more

Nerve blockPregabalinGabapentinRizatriptan

Reported Side Effects

Nerve inflammationGastrointestinal issuesRebound effectsTolerance

EditorRedditer

3.0

I’m so sorry to hear this. Taurine will help with those daytime ‘shadows’ should you be back on a cycle, and maybe see if you can get Gabapentin prescribed should that be the case.

Gabapentin

Reported Side Effects

None

Numerous-Audience180

2.0

Yeah it's a weird desperation and the mountain of anxiety waiting for it to happen. I unfortunately can't get oxygen as the doctors don't really know what they're doing. I have medical cannabis which helps a bit and sniffing apple cider vinegar can r...View more

CannabisHerbal supplementsTriptansGabapentinOxygen therapy

Reported Side Effects

DrowsinessInsomnia

CodOne5950

3.0

Yes, verapamil helps me for sure. I still have attacks most days/nights, but I no longer have the high attack volume as before. Note I do use the viles of sumatriptan mainly. I am able to abort with less- .2 or .3 - I currently am on verap and gabape...View more

VerapamilSumatriptanGabapentin

Reported Side Effects

General side effect

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