Lucent Patient

gepants

Treatment for Cluster Headache

Gepants are small molecule calcitonin gene-related peptide (CGRP) receptor antagonists that block CGRP-mediated vasodilation and neurogenic inflammation in cluster headache pathophysiology. By competitively inhibiting the CGRP receptor, gepants can reduce pain transmission and vascular changes associated with cluster headache attacks, potentially offering an alternative treatment for patients who do not respond to traditional therapies.

2.3

AVERAGE EFFICACY

CASE STUDIES

REDDIT COMMENTS

REPORTED SIDE EFFECTS

Case Studies

No case studies available.

Reddit Comments

Friendly-Channel-480

4.0

I have only been on Reddit for a few months and I have learned so much from it! I have been on Gepant shots for over 7 years and read in migraine/science that the gold standard treatment is the shots and Botox. This has been huge! This sub has also b...View more

GepantsBotoxTinted glasses

Reported Side Effects

None

Carccajou

3.0

Me too. Acupuncture did nothing. Tried a gpant once it was approved in my country, finally seeing seeing a difference. I'm sad for my past self wasting time and money and mental energy in things like acupuncture, but I was in desperation and had to d...View more

AcupunctureGepants

Reported Side Effects

General side effect

Fluffy_Salamanders

4.0

Wonderful medication. It helps my symptoms *and* makes my rescue medication more effective. The only notable side effects I have are dry mouth and a faint aftertaste of metal and burnt meat. The pills are fairly big and need more water to swallow ...View more

GepantsUbrelvy

Reported Side Effects

Dry mouthMetallic tasteBad taste

2020sbtm

4.0

I take aspirin w a cola with a gepant and that combo seems to work better than a gepant alone.

AspirinCaffeineGepants

Reported Side Effects

General side effect