Lucent Patient

h2 blocker

Treatment for Cluster Headache

H2 blockers, such as cimetidine, act by competitively inhibiting histamine H2 receptors in the gastrointestinal tract, which may indirectly modulate neurovascular inflammation and neurogenic pain pathways associated with cluster headaches. While not a primary treatment for cluster headaches, some studies suggest potential adjunctive benefits in reducing headache frequency and intensity through their anti-inflammatory and neuromodulatory effects.

4.7

AVERAGE EFFICACY

1

CASE STUDIES

7

REDDIT COMMENTS

8

REPORTED SIDE EFFECTS

Case Studies

This case study reports a 22-year-old male with simultaneous cluster headache and chronic paroxysmal hemicrania, both types of attacks responding to indomethacin treatment. The study also reviews literature on the coexistence of these two trigeminal autonomic cephalalgias.

5.0

This case study reports a 22-year-old male with simultaneous cluster headache and chronic paroxysmal hemicrania, both types of attacks responding to indomethacin treatment. The study also reviews literature on the coexistence of these two trigeminal autonomic cephalalgias.

indomethacinacetaminophennaproxentriptansrizatriptanamitriptylinecalcium channel blockersvalproatebeta blockersh2 blocker

Reddit Comments

@

icyfignewton

3.0

So I have been on it since mid 2019, started out fine at first but the past year or so I have had a hard time managing the effects on my stomach. It is super acidic and I take two 20 mg famotidines a day in addition to powdered nexium. To try to co...View more

MedicationH2 blockerProton pump inhibitors

Reported Side Effects

Stomach irritationBreakthrough symptoms

@

meglight3

4.0

Vestibular migraine is a somewhat different beast - my go-to cocktail to break a bad attack is a LOT of magnesium, anti-inflammatories, Pepcid AC, Tylenol, and a benzo. I'm not recommending benzos for long-term use but they can really help as an acut...View more

MagnesiumAnti-inflammatoryH2 blockerAcetaminophenBenzodiazepines

@

starlizzle

4.0

this happened to me too. same overall symptoms as well. i had serious gastritis, very painful. now i have gerd. don’t take PPI long term either cuz they can cause it to actually get worse and/or kill your kidneys. one thing you quickly learn as you...View more

H2 blockerHeat therapy

Reported Side Effects

Burning sensation

@

ujustcame

5.0

Me too! I am also taking omeprazole! It’s been saving my life lol. I keep seeing so much negative talk about PPIs though which concerns me.

H2 blocker