hormonal contraception
Treatment for Cluster Headache
Hormonal contraception used for Cluster Headache typically involves continuous or extended-cycle progestin-only or combined estrogen-progestin formulations that suppress ovulation and modulate hypothalamic-pituitary-gonadal axis signaling. By reducing hormonal fluctuations and stabilizing estrogen levels, these contraceptives can potentially decrease the frequency and intensity of cluster headache episodes through neuroendocrine modulation and reduction of neurogenic inflammation.