injections
Treatment for Cluster Headache
Sumatriptan injections for cluster headache act as a selective 5-HT1B/1D receptor agonist, causing vasoconstriction of cranial blood vessels and inhibiting pro-inflammatory neuropeptide release. These actions rapidly reduce neurovascular inflammation and interrupt the pain signaling cascade, providing quick relief from acute cluster headache symptoms by targeting serotonin receptors in the trigeminal system.