intravenous magnesium
Treatment for Cluster Headache
Intravenous magnesium acts as a calcium channel blocker and NMDA receptor antagonist, which helps reduce neuronal excitability and inflammation associated with cluster headaches. By modulating neuronal signaling and vasomotor tone, magnesium can potentially interrupt the pathophysiological mechanisms underlying severe headache episodes. Its administration may provide rapid relief by promoting cerebrovascular relaxation and reducing neurotransmitter release.