Lucent Patient

kanna

Treatment for Cluster Headache

Kanna (Sceletium tortuosum) acts as a serotonin reuptake inhibitor and phosphodiesterase-4 inhibitor, which may help modulate pain perception and reduce inflammation associated with cluster headaches. Its primary alkaloids, particularly mesembrine and mesembrenone, interact with serotonin receptors and exhibit anxiolytic and mood-stabilizing properties that could potentially mitigate the neurological triggers of cluster headache episodes.

2.4

AVERAGE EFFICACY

CASE STUDIES

REDDIT COMMENTS

REPORTED SIDE EFFECTS

Case Studies

No case studies available.

Reddit Comments

Xuaaka

4.0

Green Guayusa tea, brew it as strong as you can. It’s even more effective if you can grind it up like matcha. You want it like a powder; I use an electric coffee grinder followed by a manual ceramic burr grinder to get it as fine as possible. But s...View more

Guayusa teaKannaAcetyl-l-carnitineTryptophan

Reported Side Effects

General side effect

Xuaaka

4.0

I started taking 2-3 grams of the amino acid L-Tryptophan right before bed to prevent CH’s either waking me up out of me sleep and/or the beginnings of one when I wake up. It converts to Serotonin (among other things) and it feels like a mini dose o...View more

TryptophanCaffeineKanna

Reported Side Effects

General side effect

Xuaaka

5.0

I’m Chronic and I’ll get 5-6 a day if I’m not proactive. I get so many psychedelics stop working at a certain point because you build tolerance almost immediately. I’ve tried many, many things like yourself. I’ll share what’s been working for me. ...View more

CaffeineKannaTryptophan

Reported Side Effects

None

Xuaaka

4.0

I’m Chronic and I’ll get 5-6 a day as well if I’m not proactive. I really feel for you. I’ll share what’s been working for me. Green Guayusa tea, brew it as strong as you can. It’s even more effective if you can grind up like matcha. You want it ...View more

Guayusa teaPsilocybinTryptophanKanna

Reported Side Effects

General side effect