Lucent Patient

ketamine

Treatment for Cluster Headache

Ketamine, a dissociative anesthetic and NMDA receptor antagonist, acts by blocking glutamatergic neurotransmission and modulating pain perception in cluster headache treatment. Its unique pharmacological profile provides rapid analgesic effects and may interrupt the pathological neurological processes underlying cluster headache attacks by disrupting central pain signaling pathways.

3.5

AVERAGE EFFICACY

CASE STUDIES

180

REDDIT COMMENTS

217

REPORTED SIDE EFFECTS

Case Studies

Psychoactive substances as a last resort—a qualitative study of self ...

4.0

This qualitative study analyzed online forum discussions to understand how cluster headache and migraine sufferers use illicit psychoactive substances as alternative treatments when conventional medicine fails.

psychedelicslsdcannabismelatoninlidocaineketaminetaurine

Reddit Comments

None

5.0

I like fast bikes and have a ginger cat... To be totally honest if my attack reaches a 10 I do a massive dose of ketamine so it would be more a passed out look.

Ketamine

Reported Side Effects

Syncope

Jsfightingpainwpain

2.0

Hey there fellow anomaly. I’m chronic but started out as an episodic 15yrs ago. My ch is very resistant to everything my dr’s and I(mm) throw at it but am still fighting. Only thing left is the stim transplant but insurance is not covering it plus re...View more

Oxygen therapyKetamineTriptans

Reported Side Effects

Numbness

VALIS3000

4.0

I have not tried DHE, but is there are a reason you can't use oxygen? Here are some abortives not in the triptan family: Ketamine nasal spray works well for some people. Lidocaine nasal spray as pioneered by the amazing folks at UCSF Headache is a...View more

KetamineLidocaineDmtPsilocybinLsdLsa

Reported Side Effects

General side effect

negevida

3.0

My heart goes out to you. Cluster headaches was my husband's first working diagnosis (has changed multiple times since they started in January 2020). His first attacks were lasting hours and hours. Absolutely incapacitated. Pain as 11-13 on a scale...View more

CorticosteroidCalcium channel blockersTriptanOxygen therapyCombination therapyOpioidsAcupunctureChiropracticKetamineLidocaineNerve blocksInjection

Reported Side Effects

None

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