Lucent Patient

lithium

Treatment for Cluster Headache

Lithium is a mood stabilizer that may help reduce the frequency and severity of cluster headaches through its potential modulation of neurotransmitter systems and neuronal excitability. Its precise mechanism in cluster headache management is not fully understood, but it is thought to involve inhibition of excitatory neurotransmission and stabilization of neuronal membranes, potentially interrupting the pathological neurological processes underlying cluster headache attacks.

4.0

AVERAGE EFFICACY

CASE STUDIES

REDDIT COMMENTS

136

REPORTED SIDE EFFECTS

Case Studies

Cluster headache responsive to indomethacin: Case reports and a critical review of the literature

5.0

Four patients with cluster headache, some refractory to standard therapies, showed complete remission of attacks after treatment with high-dose indomethacin over one to two weeks, challenging the notion that cluster headache never responds to indomethacin.

indomethacinoxygen therapycalcium channel blockerslithium

Chronic Cluster Headache with an Atypical Presentation and Treatment Response

4.0

A 50-year-old male with chronic cluster headache presented with atypical features including pain that switched sides between attacks and occurred exclusively during sleep, showing excellent response to short cycles of lithium treatment.

oxygen therapytriptancorticosteroidcalcium channel blockerslithium

Chronic cluster headache and the pituitary gland

5.0

A 47-year-old male with chronic cluster headache was found to have a pituitary cyst and elevated prolactin levels; treatment with cabergoline (a dopamine agonist) completely resolved his cluster headaches.

dopamine agonistscalcium channel blockerstriptanslithiumantiepilepticsindomethacin

Great occipital nerve blockade for cluster headache in the emergency department: case report

3.0

This case report discusses the use of great occipital nerve blockade as a treatment for cluster headache patients presenting to the emergency department.

nerve blockstriptanscalcium channel blockersmethysergidelithium

Reddit Comments

Revlovelution

4.0

I'm sorry that you're here. I've read some good things here. First, careful with the sumatriptan, don't know if you got the injections but taking more than two a day for more than ten days will get you even more headaches. Getting frustrated d...View more

TriptansOxygen therapyCalcium channel blockersAntiepilepticsLithiumVitamin dCaffeineCorticosteroid

Reported Side Effects

Rebound headache

Short-Tooth-7419

3.0

I am chronic since 2022, and lithium worked for me for a few months

Lithium

No-Night6738

3.0

Yes. Did something but frankly not much. Probably also more useful for chronic sufferers as opposed to episodic ones. You will need continuously increasing doses to maintain relative efficacy and do bi-weekly blood tests. “Low doses” won’t make a d...View more

LithiumVerapamilVitamin d

Itchy_Mud2444

4.0

It worked for me. 10 mg lithium orotate daily. Decreases my frequency and severity by about 60%

Lithium

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