medication adjustment
Treatment for Cluster Headache
Sumatriptan, a selective serotonin receptor (5-HT1B/1D) agonist, is used for acute treatment of cluster headaches, typically administered via subcutaneous injection for rapid onset and high bioavailability. It works by causing vasoconstriction of cranial blood vessels and inhibiting neurogenic inflammation, effectively interrupting the pathophysiological cascade of cluster headache pain.