Lucent Patient

memantine

Treatment for Cluster Headache

Memantine is an NMDA receptor antagonist that modulates glutamatergic neurotransmission, potentially reducing neurogenic inflammation and central sensitization associated with cluster headaches. By blocking excessive glutamate-mediated excitatory signaling, memantine may help prevent or reduce the frequency and intensity of cluster headache attacks, offering an alternative treatment option for patients with refractory symptoms.

3.3

AVERAGE EFFICACY

CASE STUDIES

REDDIT COMMENTS

REPORTED SIDE EFFECTS

Case Studies

No case studies available.

Reddit Comments

poppypurple

3.0

I tried topiramate, nadolol, namenda, amitriptyline, and I think two other oral meds to prevent migraines. Some would work for a while, but then the pain would come back. I have been taking ajovy for a few years and it helped, but then this spring ...View more

AntiepilepticsNadololMemantineAmitriptylineFremanezumabBotoxTriptansUbrelvy

Reported Side Effects

Reversible side effects

mindfluxx

3.0

Botox sounds next. Or could double up on preventative drugs. I am on Botox, ajovy and memantine.

BotoxFremanezumabMemantine

Reported Side Effects

General side effect

mindfluxx

4.0

So I found lots of meds only gave me very minor improvements ( I was daily for a couple years ). Backbone of my current treatments is Botox, every 10 weeks. I also take ajovy, and memantine. I only get a few per month now and they are much less seve...View more

BotoxCgrp inhibitorsMemantine

sgsduke

3.0

Hey hey hey 5 years daily migraine here to offer advice. CGRP inhibitors! There are injectable monthly preventatives like Emgality and Ajovy, there's a monthly infusion Vyepti, and there are abortive tablets, Nurtec and Ubrelvy. This is not an exha...View more

EmgalityCgrp antagonistPregabalinPropranololLidocaineCbdCold therapyZofranMemantineTrigger point injectionsAcupuncture

Reported Side Effects

General side effect

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