Lucent Patient

meperidine

Treatment for Cluster Headache

Meperidine is a synthetic opioid analgesic that acts primarily as a μ-opioid receptor agonist, providing rapid pain relief for cluster headaches by binding to central nervous system receptors and modulating pain perception. Its mechanism involves inhibiting neurotransmitter release and reducing neurogenic inflammation, which can help interrupt the intense pain characteristic of cluster headache episodes.

2.4

AVERAGE EFFICACY

CASE STUDIES

REDDIT COMMENTS

REPORTED SIDE EFFECTS

Case Studies

No case studies available.

Reddit Comments

Writer_Brain1811

2.0

No alcohol. No movies. No concerts, Nothing with loud noises, flashing lights, etc. Pools, beaches, golf courses - no bright sunlight. I have had migraines since my late teens (50+ years). For most of that time there was nothing but aspirin, ibup...View more

AspirinIbuprofenMeperidine

PupperPuppet

2.0

This was how it worked for my entire childhood. At most during those years I'd have to go to the ER for a migraine once a month, more usually every two or three months. Doctors simply refused to believe a five or seven or thirteen year old could po...View more

Meperidine

None

4.0

For me at one point: 150mg Meperidine I.M. and 0.5-1.0mg I.M Dexamethasone were very helpful in aborting a migraine for me at home. The Demerol dose is high. But it’s what’s works for each of us. Demerol hits k-opioid receptors and is less potent th...View more

MeperidineCorticosteroid

gurl_unmasked

4.0

I went before I was officially diagnosed. It was my first migraine and I went on day 4, after trying everything OTC. I was given IV Demerol and a scan of my brain. I was d/c with a script for hydrocodone (I think-this was 20 years ago) and instructed...View more

MeperidineHydrocodoneFioricet

Reported Side Effects

General side effect