Lucent Patient

metformin

Treatment for Cluster Headache

Metformin, primarily an antidiabetic medication, has shown potential in cluster headache management through its ability to modulate mitochondrial function and reduce neuroinflammation. By activating AMP-activated protein kinase (AMPK) and improving mitochondrial bioenergetics, metformin may help reduce the frequency and intensity of cluster headache episodes through neuroprotective and metabolic regulatory mechanisms.

3.4

AVERAGE EFFICACY

CASE STUDIES

REDDIT COMMENTS

REPORTED SIDE EFFECTS

Case Studies

No case studies available.

Reddit Comments

No-Delivery549

4.0

Yes, it was insulin resistance in my case. I had migraine symptoms for over 15 years at the time and clear insulin resistance symptoms for at least 5 years, however I suspect it that they were earlier masked by sport. Still, having noted in my medic...View more

Hormone therapyMetforminMuscle relaxantsAnalgesic

PoppyRyeCranberry

4.0

Just wanted to jump in this thread because I also have a primary trigger related to my blood sugar and two of the things that were critical to prevention for me were suppressing my cycle with continuous combo birth control and metformin to regulate m...View more

Birth controlMetforminDietary modification

PoppyRyeCranberry

5.0

I have a huge menstrual trigger and also used to get triggered by barometric pressure changes. I prevent the menstrual migraines by suppressing my cycle with continuous dose combo bc (other women on the sub do it with progestin-only bc), and my pres...View more

Birth controlBotoxMetformin

Reported Side Effects

None

No-Delivery549

4.0

I was even diagnosed with advanced insulin resistance and prediabetes on top of it. I was quite surprised and sad about it, because I thought that I already took good care of my health. It took a bit of time to adjust, but I'm very happy with my adju...View more

Metformin

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