Lucent Patient

methylphenidate

Treatment for Cluster Headache

Methylphenidate, a central nervous system stimulant, acts primarily by inhibiting dopamine and norepinephrine reuptake, which may help modulate pain perception and neurological signaling in cluster headache. Its sympathomimetic properties and potential to enhance descending pain inhibitory pathways can provide relief by altering neural transmission and potentially reducing the frequency and intensity of cluster headache episodes.

4.3

AVERAGE EFFICACY

CASE STUDIES

REDDIT COMMENTS

REPORTED SIDE EFFECTS

Case Studies

Methylphenidate as a potential treatment for cluster headache

4.0

A 30-year-old man with chronic, refractory cluster headache experienced a complete cessation of attacks for two weeks and a sustained reduction from five attacks per day to about five per week after starting methylphenidate for comorbid ADHD.

methylphenidate

CASE REPORT: CLUSTER HEADACHE MANAGEMENT WITH METHYLPHENIDATE (RITALIN)

5.0

A case report of a 43-year-old male with a 5-year history of cluster headaches refractory to standard treatments who experienced complete headache relief within 10 minutes of taking methylphenidate (Ritalin), with prophylactic dosing preventing future episodes.

methylphenidate

Methylphenidate for Chronic Migraine and Cluster-Type Headaches: A Case Report | Request PDF

4.0

Multiple case studies and trials examining the use of methylphenidate and dextroamphetamine for treating cluster headaches, migraines, and chronic fatigue syndrome, showing promising results for these stimulant medications as repurposed treatments for headache disorders.

methylphenidateamphetaminessribupropion

Cluster Headache Management With Methylphenidate (Ritalin)

5.0

A 43-year-old man with a 5-year history of refractory cluster headache experienced complete headache relief within 10 minutes of a 10 mg dose of methylphenidate and prevention of nightly attacks with once-daily dosing, with a week of therapy halting his cluster series. This is the first reported case of methylphenidate providing both abortive and prophylactic benefit in cluster headache.

methylphenidate

Reddit Comments

hakboy81

3.0

## Heavy cluster attacks and something that seems to work for me I have a long history of cluster headaches and am also diagnosed with add. I tried al the options available, but what seems to help is taking ritalin as the attack starts. Are more of y...View more

Methylphenidate

PuzzledTaste3562

4.0

This is completely new to me, but I did see a lot of evidence that methylphenidate (Ritalin) helps abort CH attacks and even migraine. Search engines return a lot of results, including academic sources and clusterbusters.org. Whilst this is great ne...View more

Methylphenidate

Reported Side Effects

Addiction risk

hakboy81

3.0

It seems to work the same as drinking loads of Red Bull. But I mostly have to puke after those loads of energy drink. And the side effects are the same. Racing hart, not being able to sleep and some depression like effect. But I found it ritalin/adde...View more

CaffeineMethylphenidateAmphetamineOxygen therapyCalcium channel blockers

Reported Side Effects

TachycardiaInsomniaDepressionVomiting

ProcessRare3733

4.0

Yes! My methylphenidate helped in my last cluster period. (technically still chronic as the months long nightmare ended 2 weeks ago) When I went off methylphenidate it got more intense and even more frequent so I’m positive the mechanism of action is...View more

Methylphenidate

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