Lucent Patient

nitrous oxide

Treatment for Cluster Headache

Nitrous oxide acts as an NMDA receptor antagonist and releases endogenous opioids, providing rapid analgesic and anxiolytic effects for cluster headaches. When inhaled at high concentrations (typically 50-70%), it can quickly interrupt the neurogenic inflammatory cascade and provide significant pain relief for patients experiencing acute cluster headache episodes.

2.8

AVERAGE EFFICACY

CASE STUDIES

REDDIT COMMENTS

REPORTED SIDE EFFECTS

Case Studies

No case studies available.

Reddit Comments

n7shepart

4.0

I use the oxygen the same way I used gas and air when I was in labour. When the pain gets really strong I take the deepest breath in of oxygen through the mask, breathe out, and again until that particular cluster is over stop breathing the oxygen th...View more

Oxygen therapyNitrous oxideCaffeineVitamin d

Reported Side Effects

Headache

Kindly-Cover-5406

5.0

The only thing I use and recommend is magic mushrooms. It stops my cycle completely and has prevented cycles from starting. High Flow Oxygen also works pretty effectively on attacks. Gas and Air worked on me very quickly when I had to call an ambula...View more

PsilocybinOxygen therapyNitrous oxide

Reported Side Effects

Symptom worsening

Kindly-Cover-5406

1.0

I hear ya. I’ve tried virtually every painkiller I could get from Paracetamol to Morphine and I’ve tried all sorts of combinations and even taking them hours in advance when anticipating an attack and nothing worked. Painkillers just wont touch it. T...View more

AcetaminophenOpioidsNitrous oxideOxygen therapyVerapamilSumatriptanPsilocybin

Kindly-Cover-5406

5.0

Triptans made my cycles horrific and unbearable. I went from one or occasionally two just about bearable 30 - 60 minute attacks per day, usually around the same time of day for around 6 - 8 weeks to 8 or 10 random attacks per day, lasting anything up...View more

Nitrous oxide