not a treatment
Treatment for Cluster Headache
Ketamine, a dissociative anesthetic and NMDA receptor antagonist, has shown potential in rapidly alleviating cluster headache symptoms by modulating glutamatergic neurotransmission and interrupting pain signaling pathways. Its unique mechanism involves blocking glutamate receptors, reducing neuronal excitability, and potentially resetting aberrant pain circuits associated with cluster headache pathophysiology.