Lucent Patient

orphenadrine

Treatment for Cluster Headache

Orphenadrine is a centrally-acting anticholinergic and antihistamine medication with muscle relaxant properties that may help modulate pain perception and reduce muscle tension in cluster headaches. By antagonizing muscarinic acetylcholine receptors and potentially influencing dopaminergic pathways, it can provide mild analgesic and muscle relaxant effects that may help mitigate the intense pain associated with cluster headache episodes.

2.1

AVERAGE EFFICACY

CASE STUDIES

REDDIT COMMENTS

REPORTED SIDE EFFECTS

Case Studies

No case studies available.

Reddit Comments

Longjumping-Ad-9541

2.0

Chronic for 15 years, lifelong sufferer. To be honest, many days I am not particularly functional. I do have a accommodations and formal intermittent FMLA at work so nobody can give me shit about missing more than the 1.25 days / month allotted (1...View more

BotoxPregabalinSumatriptanZavzpretNsaidsOrphenadrine

Reported Side Effects

General side effect

Lonely_Pop2077

1.0

## Intractable migraine and losing hope Hello all, I just needed to get this to the world where people would understand. I have had an intractable migraine for at least a month on a pain scale of a 6/7 every day, with no remit. It gets progressively ...View more

ErenumabBotoxMethylprednisoloneMorphineUnknown medicationOrphenadrineCorticosteroidsSumatriptanPiroxicamAntihistaminesIbuprofenAcetaminophenFioricetVitamin supplement

Reported Side Effects

None

migrainemonster

4.0

I have had a lot of neck pain associated with migraines. I started cymbalta in the spring which made a big difference in overall pain and then I changed muscle relaxers from zanaflex to orphenadrine. The orphenadrine is really very effective. I have ...View more

DuloxetineOrphenadrineBotox

Reported Side Effects

General side effect

migrainemonster

4.0

It did help somewhat, but my neck tension is apparently very bad, so it didn't knock it out completely and I was on zanaflex at the time too. However, I was having a lot of facial pain and nerve symptoms in my tongue and lips and that went away. But ...View more

DuloxetineTizanidineOrphenadrine

Reported Side Effects

NauseaRash