otc medication
Treatment for Cluster Headache
Sumatriptan, a selective serotonin receptor (5-HT1B/1D) agonist, rapidly constricts cranial blood vessels and inhibits neuropeptide release, effectively interrupting the neurogenic inflammation associated with cluster headaches. When administered via subcutaneous injection or nasal spray, it provides fast-acting relief by targeting the trigeminal-vascular system and reducing pain signaling.