oxycodone
Treatment for Cluster Headache
Oxycodone, a semisynthetic opioid analgesic, acts as a full μ-opioid receptor agonist in the central nervous system, modulating pain perception and reducing nociceptive signaling. In cluster headache treatment, it provides rapid pain relief by binding to opioid receptors, decreasing neuronal excitability and potentially interrupting the intense pain associated with these headaches.