ozempic
Treatment for Cluster Headache
Ozempic (semaglutide), a GLP-1 receptor agonist primarily used for diabetes management, has shown potential off-label benefit in cluster headache treatment by modulating neuroinflammatory pathways and potentially reducing trigeminal nerve sensitization. Its mechanism likely involves decreasing CGRP (calcitonin gene-related peptide) release and attenuating neurogenic inflammation, which may contribute to reducing the frequency and intensity of cluster headache episodes.