pain management
Treatment for Cluster Headache
Sumatriptan, a selective serotonin 5-HT1B/1D receptor agonist, rapidly constricts cranial blood vessels and inhibits pro-inflammatory neuropeptide release in cluster headache treatment. When administered subcutaneously or via nasal spray, it effectively reduces pain intensity and duration by targeting serotonergic pathways in the trigeminal system. Its fast-acting mechanism provides rapid symptomatic relief during acute cluster headache episodes.