pain medication
Treatment for Cluster Headache
Sumatriptan, a selective serotonin receptor agonist (5-HT1B/1D), acts by vasoconstricting cerebral blood vessels and inhibiting pro-inflammatory neuropeptide release in the trigeminovascular system, effectively interrupting the pathophysiological cascade of cluster headaches. Its rapid onset of action and ability to cross the blood-brain barrier allow for quick relief of acute cluster headache symptoms by modulating neurotransmitter activity and reducing neurogenic inflammation.