Potassium supplementation in Cluster Headache management is thought to modulate neuronal membrane potential and ion channel function, potentially reducing neuronal hyperexcitability. By helping to stabilize neuronal membranes and potentially influencing neurotransmitter release, potassium may help mitigate the intense, short-duration pain characteristic of cluster headaches. However, its precise mechanism in headache pathogenesis is not fully elucidated and requires further research.