propranolol
Treatment for Cluster Headache
Propranolol is a non-selective beta-blocker that reduces neuronal excitability and modulates sympathetic nervous system activity, potentially decreasing the frequency and intensity of cluster headache episodes. By blocking beta-1 and beta-2 adrenergic receptors, it reduces vascular reactivity and neurogenic inflammation, which may contribute to its prophylactic effect in cluster headache management.
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REPORTED SIDE EFFECTS