rescue medication
Treatment for Cluster Headache
Sumatriptan, a selective serotonin 5-HT1B/1D receptor agonist, is the primary rescue medication for acute cluster headache treatment. It rapidly constricts cranial blood vessels and inhibits pro-inflammatory neuropeptide release, providing fast pain relief and reducing the intensity of cluster headache symptoms through its vasoconstrictive and neurotransmitter-modulating properties.