rotigotine
Treatment for Cluster Headache
Rotigotine is a non-ergot dopamine agonist that acts primarily on D2 and D3 receptors in the central nervous system, which can help modulate pain perception and neurotransmitter signaling in cluster headache. By stimulating dopaminergic pathways, rotigotine may reduce the frequency and intensity of cluster headache attacks through its neuromodulatory effects on pain processing and autonomic regulation.