schedule modification
Treatment for Cluster Headache
Sumatriptan, a selective serotonin receptor (5-HT1B/1D) agonist, rapidly alleviates cluster headache symptoms by causing vasoconstriction and inhibiting neurogenic inflammation in cerebral blood vessels. When administered via subcutaneous injection, it provides rapid onset of action and significant pain relief within 10-15 minutes, making it a first-line acute treatment for cluster headache episodes.