Lucent Patient

semaglutide

Treatment for Cluster Headache

Semaglutide, a GLP-1 receptor agonist, is being investigated for potential off-label use in Cluster Headache management, with emerging evidence suggesting it may modulate neuroinflammatory pathways and neuropeptide signaling. By activating GLP-1 receptors in the brain and potentially reducing calcitonin gene-related peptide (CGRP) levels, semaglutide may help decrease headache frequency and intensity in cluster headache patients.

2.7

AVERAGE EFFICACY

CASE STUDIES

REDDIT COMMENTS

REPORTED SIDE EFFECTS

Case Studies

No case studies available.

Reddit Comments

cioncaragodeo

1.0

Same. Near 40 lbs in 3 months. I had to add ozempic, and now topamax, to counter it. I'm meeting with my neuro shortly and kinda want off everything since nothing impacted my migraines.

SemaglutideAntiepileptics

Reported Side Effects

Weight gain

DanFanell

4.0

I noticed the same thing when I started taking Ozempic for PCOS. I was switched to Wegovy this year when my insurance stopped covering it because I am not Type II diabetic. When first starting or with any dose increase, I would get an “Ozempic headac...View more

OzempicSemaglutidePropranololBotox

Reported Side Effects

Headache

salamandas411

4.0

Wegovy helped me too. I was more stable, I could lose weight without triggering migraines, and my fibromyalgia was better. Then my insurance decided it was going to cost $750/month. It used to be $60.

Semaglutide

Reported Side Effects

General side effect

broccoli-1

1.0

I've lost 15 kg since July with the help of daily semaglutide pills (small 3 mg dosage) and my migraines have only gotten worse lol. My insuline resistance has improved as well as some other health markers but my migraines haven't budged one bit :/

Semaglutide

Reported Side Effects

General side effect