sleep aid
Treatment for Cluster Headache
Melatonin acts as a chronobiotic agent that helps regulate sleep-wake cycles and may reduce the frequency and intensity of cluster headache attacks by modulating circadian rhythms and providing neuroprotective effects. Its primary mechanism involves binding to melatonin receptors (MT1 and MT2) in the central nervous system, which can decrease neuronal excitability and provide analgesic properties that may help mitigate cluster headache symptoms.