sleep schedule
Treatment for Cluster Headache
Melatonin acts as a chronobiotic agent that helps regulate circadian rhythms and has potential therapeutic effects in cluster headache by modulating sleep-wake cycles and reducing neurogenic inflammation. Its primary mechanism involves binding to melatonin receptors MT1 and MT2 in the hypothalamus, which can help normalize disrupted circadian patterns and potentially reduce the frequency and intensity of cluster headache episodes.