trigger identification
Treatment for Cluster Headache
Psilocybin, a serotonergic psychedelic, acts as a partial agonist at 5-HT2A receptors, modulating neural connectivity and potentially interrupting pathological pain circuits associated with cluster headaches. Its mechanism involves neuroplastic changes and altered brain network dynamics, which may help reset aberrant neural patterns and provide prophylactic or acute relief from cluster headache episodes.