Lucent Patient

triptan nsaid combination

Treatment for Cluster Headache

Triptans (5-HT1B/1D receptor agonists) constrict cranial blood vessels and inhibit neuropeptide release, while NSAIDs reduce inflammatory mediators and prostaglandin synthesis. This combination provides dual-action pain relief by targeting both vascular and inflammatory mechanisms associated with cluster headache pathophysiology, potentially offering more comprehensive symptom management.

2.4

AVERAGE EFFICACY

CASE STUDIES

REDDIT COMMENTS

REPORTED SIDE EFFECTS

Case Studies

No case studies available.

Reddit Comments

harper2233

5.0

I’m sorry. Sumatriptan/naproxen was the only abortive that worked for me so I was in a similar situation with severe chronic migraine. Then I started ajovy - I’m on month 3 now and it’s been an absolute life saver.

Triptan nsaid combinationFremanezumab

Reported Side Effects

General side effect

Kali711

3.0

I was just given the combo pill of sumtriptan + naproxen. It definitely takes the pain away, but I'll stay with the other symptoms (dizziness/vertigo, nausea, light/noise sensitivity). But still progress!

Triptan nsaid combination

Reported Side Effects

General side effect

MauriceMossIsTheBoss

3.0

Finding the right Magnesium supplement Had my daith pierced by a friend Sometimes hot shower then ice pack Sumatriptan ASAP + NSAID if all else fails

MagnesiumDaith piercingContrast therapyTriptan nsaid combination

Reported Side Effects

General side effect

PoppyRyeCranberry

4.0

There are studies showing combining a triptan with an NSAID is superior to either alone. My doctor recommends 800mg of Ibuprofen with my triptan, but the studies cited below used 500 mg of naproxen sodium (Aleve). https://pubmed.ncbi.nlm.nih.gov/1...View more

Triptan nsaid combinationCombination therapy

Reported Side Effects

General side effect