Lucent Patient

venlafaxine

Treatment for Cluster Headache

Venlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI) that modulates neurotransmitter activity in the central nervous system, potentially reducing neurogenic inflammation and pain signaling associated with cluster headaches. By increasing synaptic concentrations of serotonin and norepinephrine, it may help stabilize neural pathways and provide prophylactic management of cluster headache episodes through its neuromodulatory effects.

3.2

AVERAGE EFFICACY

CASE STUDIES

142

REDDIT COMMENTS

200

REPORTED SIDE EFFECTS

Case Studies

No case studies available.

Reddit Comments

j_robbins_21

4.0

So, honestly, I’m not really sure. It could be that the verapamil stopped the hyperalgesic feedback loop so he is only getting mild attacks now, but the autonomic facial symptoms are still there. It could also be that his cycle is almost completely o...View more

VerapamilVenlafaxineEmgality

Different-Corgi-2999

2.0

Starting Emgality on Monday. I was on Paxil for 20 years for anxiety and I thought I had pooped out on the medicine. My doctor switched me to Effexor. That’s when my headaches and migraines started. He’s switched me back and I am doing a cross taper....View more

Cgrp inhibitorsAntidepressantsVenlafaxine

Reported Side Effects

Headache

cro78

2.0

## Anyone else have constant shadows? Treatments? So my cluster headaches started over 20 years ago. At first they would be ‘typical’ in that the pain would ramp up to 10/10 (always upper left corner of right eye) stabbing pain and then go back down ...View more

VenlafaxineAnticonvulsantsPsychedelics

j_robbins_21

4.0

Hey thanks for the response. I tried the Ritalin route for about a month. The reason I started it was because the cluster headache pain was well controlled by emgality but the brain fog and exhaustion was not. I was prescribed concerta 18mg and I had...View more

MethylphenidateCgrp inhibitorsVenlafaxine

Reported Side Effects

Cognitive impairment

...