vitamin b12
Treatment for Cluster Headache
Vitamin B12 (cobalamin) in cluster headache treatment acts primarily by supporting mitochondrial energy metabolism and reducing neuroinflammation. Its mechanism involves enhancing cellular energy production, improving neuronal function, and potentially modulating neurotransmitter pathways that may contribute to headache pathogenesis. High-dose vitamin B12 supplementation has shown potential in reducing headache frequency and intensity by supporting neurological health and potentially mitigating oxidative stress.