weight loss
Treatment for Cluster Headache
Topiramate acts as an anticonvulsant and migraine prophylactic with potential efficacy in cluster headache treatment by modulating neuronal excitability through voltage-dependent sodium channel blockade and enhancing GABA-ergic neurotransmission. Its weight loss effect is mediated by suppressing appetite, increasing satiety, and potentially inhibiting carbonic anhydrase, which may reduce insulin secretion and lipogenesis.