zomitriptan
Treatment for Cluster Headache
Zolmitriptan is a selective 5-HT1B/1D receptor agonist that acts on serotonin receptors in cerebral blood vessels, causing vasoconstriction and inhibiting neurogenic inflammation. When used for cluster headache, it rapidly reduces pain by constricting cranial blood vessels and blocking pain signal transmission in the trigeminal nerve, providing quick relief from acute headache symptoms.