Clonidine is an α2-adrenergic agonist that modulates central nervous system neurotransmission by reducing norepinephrine release, which can potentially mitigate hyperexcitability in neural circuits associated with Visual Snow Syndrome. By dampening sympathetic nervous system activity and providing neuroprotective effects, clonidine may help reduce visual disturbances and neurological symptoms through its centrally acting sympatholytic properties.